in press
Stegmann, Y., Schiele, M., Schümann, D., Lonsdorf, T.B., Zwanzger, P., Romanos, M., Reif, A., Domschke, K., Deckert, )J., Gamer, M., & Pauli, P. Individual Differences in Human Fear Generalization – Pattern Identification and Implications for Anxiety Disorders, Translational Psychiatry (in press)
Domschke, K., Gottschalk, M., Richter, J., Ziegler, C., Schiele, M., Mann, M., Geiger, M., Schartner, C., Homola, G., Alpers, G., Büchel, C., Fehm, L., Fydrich, T., Gerlach, A., Gloster, A., Helbig-Lang, S., Kalisch, R., Kircher, T., Lang, T., Lonsdorf, T.B., Pané-Farré, C., Ströhle, A., Weber, H., Zwanzger, P., Arolt, V., Romanos, M., Wittchen, H-U., Hamm, A., Pauli, P., Reif, A., Deckert, J., Neufang, S. & Hoefler, M., Orexin in the anxiety spectrum: Association of a HCRTR1 polymorphism with panic disorder/agoraphobia, CBT treatment response and fear-related intermediate phenotypes, Translational Psychiatry (in press)
Bauer, E., McNamara, A-M., Sandree, A., Lonsdorf, T.B., Weinberg, A., Morris, J. & VanReekum C. Intolerance of Uncertainty and Threat Generalization: A Replication and Extension (Psychophysiology, accepted)
preprints
Ehlers, M., Nold, J., Kuhn, M., Klingelhöfer-Jens, M. & Lonsdorf, T.B., Natural variations in brain morphology do not account for inter-individual differences in defensive responding during fear acquisition training and extinction, PsyArXiv, https://psyarxiv.com/q2kyf/
Sjouwerman, R., Scharfenort, R. & Lonsdorf, T.B. Individual differences in predicting fear: Specificity to trait anxiety and mediation via amygdala activation (in revision), BioRxiv: https://www.biorxiv.org/content/10.1101/233528v2
Sjouwerman, R. & Lonsdorf, T.B. Experimental boundary conditions of reinstatement induced return of fear in humans: intensity of reinstatement (in revision); preprint: https://psyarxiv.com/4myk8
key publications
Lonsdorf, T. B., Klingelhöfer-Jens, M., Andreatta, M., Beckers, T., Chalkia, A., Gerlicher, A., Haaker, J., Jentsch, V., Meir Drexler, S., Mertens, G., Richter, J., Sjouwerman, R. & Wendt, J. & Merz, C. J. (2019) Navigating the garden of forking path for data exclusion in fear conditioning research. Elife, e52465
Haaker, J., Maren, S., Andreatta, M., Merz, C.J., Richter, J., Richter, H., Meir Drexler, S., Lange, M., KJüngling, K., Nees, F.,
Seidenbecher, T., Fullana, M.A., Wotjak C., & Lonsdorf, T. B. (2019) Making translation work: Harmonizing cross-species methodology in the behavioural neuroscience of Pavlovian fear conditioning. Neuroscience Biobehavioral Reviews, 107:329-345
Lonsdorf, T.B., Menz M.M., Andreatta, Fullana, M.A., Golkar, A., Haaker, J., Heitland, I, Hermann, A., Kuhn, M., Kruse, O.,, Meir- Drexler, S., Meulders, A., Nees, F., Pittig, A., Richter, J., Römer, S., Shiban, J., Schmitz, A., Benjamin Straube, B., Vervliet, B., Wendt, J., Baas, J. & Merz, C.J., Don’t fear ‘fear conditioning’: Methodological considerations for the design and analysis of studies on human fear acquisition, extinction, and return of fear, Neurocience and Biobehavioral Reviews, 77:247-285.
Lonsdorf, T.B. & Merz, C.J. (2017) More than just noise: Individual differences in fear acquisition, extinction and return of
fear in humans – Biological, experiential, temperamental factors, and methodological pitfalls, Neurocience and Biobehavioral Reviews, 80:703-728
Sjouwerman, R., Kuhn, M., Niehaus, J. & Lonsdorf, T.B. Don’t startle me – Interference of startle probe presentations and intermittent ratings with fear acquisition. Psychophysiology, 53(12):1889-1899. doi: 10.1111/psyp.12761
Lonsdorf T.B.*, Haaker J* & Kalisch R. (2014) Long-term expression of human contextual fear and extinction memories involves amygdala, hippocampus and ventromedial prefrontal cortex: a reinstatement study in two independent samples. Social Cognitive and Affective Neuroscience, 9(12):1973-83.
Haaker J., Gaburro S., Sah A., Gartmann N., Lonsdorf T.B., Meier K., Singewald N., Pape H-C., Morellini F. * & Kalisch R..* (2013). A single dose of L-DOPA makes extinction memories context-independent and prevents the return of fear. Proceedings of the National Academy of Sciences (PNAS), 110(26):E2428-36
Lonsdorf T.B., Weike A.I., Nikamo P., Schalling M., Hamm A.O. & Ohman A. (2009). Genetic Gating of Human Fear Learning and Extinction: Possible Implications for Gene-Environment Interaction in Anxiety Disorder. Psychological Science, 20(2), 198-206.