in press
Haaker, J., Maren, S., Andreatta, M., Merz, C.J., Richter, J., Richter, H., Meir Drexler, S., Lange, M., KJüngling, K., Nees, F., Seidenbecher, T., Fullana, M.A., Wotjak C., & Lonsdorf, T. B. Making translation work: Harmonizing cross-species methodology in the behavioural neuroscience of Pavlovian fear conditioning. Neuroscience Biobehavioral Reviews (accepted)
Kuhn, M., Wendt, J., Sjouwerman, R., Büchel, C., Hamm, A., & Lonsdorf, T.B., The neurofunctional basis of affective startle modulation in humans – evidence from combined facial EMG-fMRI, Biological Psychiatry (in press) [link to post-print]
Stegmann, Y., Schiele, M., Schümann, D., Lonsdorf, T.B., Zwanzger, P., Romanos, M., Reif, A., Domschke, K., Deckert, )J., Gamer, M., & Pauli, P. Individual Differences in Human Fear Generalization – Pattern Identification and Implications for Anxiety Disorders, Translational Psychiatry (in press)
Domschke, K., Gottschalk, M., Richter, J., Ziegler, C., Schiele, M., Mann, M., Geiger, M., Schartner, C., Homola, G., Alpers, G., Büchel, C., Fehm, L., Fydrich, T., Gerlach, A., Gloster, A., Helbig-Lang, S., Kalisch, R., Kircher, T., Lang, T., Lonsdorf, T.B., Pané-Farré, C., Ströhle, A., Weber, H., Zwanzger, P., Arolt, V., Romanos, M., Wittchen, H-U., Hamm, A., Pauli, P., Reif, A., Deckert, J., Neufang, S. & Hoefler, M., Orexin in the anxiety spectrum: Association of a HCRTR1 polymorphism with panic disorder/agoraphobia, CBT treatment response and fear-related intermediate phenotypes, Translational Psychiatry (in press)
under review/in revision
Sjouwerman, R. & Lonsdorf, T.B. Experimental boundary conditions of reinstatement induced return of fear in humans: intensity of reinstatement (Psychophysiology, in revision)
Bauer, E., McNamara, A-M., Sandree, A., Lonsdorf, T.B., Weinberg, A., Morris, J. & VanReekum C. Intolerance of Uncertainty and Threat Generalization: A Replication and Extension (Psychophysiology, in revision)
preprints
Lonsdorf, T. B., Klingelhöfer-Jens, M., Andreatta, M., Beckers, T., Chalkia, A., Gerlicher, A., Haaker, J., Jentsch, V., Meir Drexler, S., Mertens, G., Richter, J., Sjouwerman, R. & Wendt, J. & Merz, C. J. How to not get lost in the garden of forking paths: Lessons learned from human fear conditioning research regarding exclusion criteria. PsyArXiv, https://doi.org/10.31234/osf.io/6m72g
Sjouwerman, R., Scharfenort, R. & Lonsdorf, T.B. Individual differences in predicting fear: Specificity to trait anxiety and mediation via amygdala activation, BioRxiv
key publications
Kuhn, M., Wendt, J., Sjouwerman, R., Büchel, C., Hamm, A., & Lonsdorf, T.B., The neurofunctional basis of affective startle modulation in humans – evidence from combined facial EMG-fMRI, Biological Psychiatry (in press) [link to post-print]
Lonsdorf, T.B., Merz, C.J. & Fullana, M.A., (2019) Extinction retention – is it what we think it is? Biological Psychiatry [link to post-print]
Lonsdorf, T.B., Menz M.M., Andreatta, Fullana, M.A., Golkar, A., Haaker, J., Heitland, I, Hermann, A., Kuhn, M., Kruse, O.,, Meir- Drexler, S., Meulders, A., Nees, F., Pittig, A., Richter, J., Römer, S., Shiban, J., Schmitz, A., Benjamin Straube, B., Vervliet, B., Wendt, J., Baas, J. & Merz, C.J., Don’t fear ‘fear conditioning’: Methodological considerations for the design and analysis of studies on human fear acquisition, extinction, and return of fear, Neurocience and Biobehavioral Reviews, 77:247-285.
Lonsdorf, T.B. & Merz, C.J. (2017) More than just noise: Individual differences in fear acquisition, extinction and return of fear in humans – Biological, experiential, temperamental factors, and methodological pitfalls, Neurocience and Biobehavioral Reviews
Deckert J., Weber, H., Villmann, C., Lonsdorf, T.B., Richter, J., Andreatta, M., Arias-Vasquez, A., Hommers, L., Kent, L., Schartner, C., Cichon, S., Schaefer, N., von Collenberg, C.R., Wachter, B., Blum, R., Schümann, D., Scharfenort, R., Schumacher, J., Forstner, A.J., Baumann, C., Schiele, M., Notzon, S., Zwanzger, P., Janzing, J.G.E., Galesloot, T., Kiemeney, L.A., Gajewska, A., Glotzbach-Schoon, E., Mühlberger, A., lpers, G., Fydrich, T., Fehm, L., Gerlach, A.L., Kircher, T., Lang, T., Ströhle, A., Arolt, V., Wittchen, H-U., Kalisch, R., Büchel, C., Hamm, A., Nöthen, M.M., Romanos, M., Domschke, K., Pauli, P. & Reif, A. GLRB allelic variation predisposes to agoraphobia by increasing startle response. Molecular Psychiatry, (in press) doi:10.1038/mp.2017.2
Sjouwerman, R., Kuhn, M., Niehaus, J. & Lonsdorf, T.B. Don’t startle me – Interference of startle probe presentations and intermittent ratings with fear acquisition. Psychophysiology, 53(12):1889-1899. doi: 10.1111/psyp.12761.
Kuhn, M., Scharfenort, R., Schümann, D., Schiele, M., Münsterkötter, A.L., Domschke, K., Haaker, J., Kalisch, R., Pauli, P., Reif, A., Zwanzger, P. & Lonsdorf, T.B. Mismatch or allostatic load? Timing of life-adversity differentially shapes gray matter volume and anxious-temperament Social Cognitive and Affective Neuroscience 11(5):803-12
Scharfenort, R., Menz, M. M. & Lonsdorf, T.B. (2016) Adversity-induced relapse of fear – Neural Mechanisms and implications for relapse prevention from a study on experimentally induced return- of- fear following fear conditioning and extinction. Translational Psychiatry, 19, 6:e858, doi: 10.1038/tp.2016.126
Lonsdorf T.B.*, Haaker J* & Kalisch R. (2014) Long-term expression of human contextual fear and extinction memories involves amygdala, hippocampus and ventromedial prefrontal cortex: a reinstatement study in two independent samples. Social Cognitive and Affective Neuroscience, 9(12):1973-83.
Haaker J., Gaburro S., Sah A., Gartmann N., Lonsdorf T.B., Meier K., Singewald N., Pape H-C., Morellini F. * & Kalisch R..* (2013). A single dose of L-DOPA makes extinction memories context-independent and prevents the return of fear. Proceedings of the National Academy of Sciences (PNAS), 110(26):E2428-36
Lonsdorf T.B., Rueck C., Bergström J. Andersso, G., Öhman A., Lindefors N. & Schalling M. (2010). The COMTval158met polymorphism affects efficacy of exposure based CBT in panic patients. BMC Psychiatry, 10:99doi:10.1186/1471-244X-10-99.
Lonsdorf T.B., Weike A.I., Nikamo P., Schalling M., Hamm A.O. & Ohman A. (2009). Genetic Gating of Human Fear Learning and Extinction: Possible Implications for Gene-Environment Interaction in Anxiety Disorder. Psychological Science, 20(2), 198-206.